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HPLC

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Analysis of Pharmaceuticals with UltraSep ES PHARM

UltraSep ES PHARM

UltraSep ES PHARM and UltraSep ES PHARM SPEZIAL are high selective HPLC-packings, first of all developed to analyze pharmaceutical products, which are often very polar and strong basic. The extreme small content of metallic ions in these packings must be pointed out. With such columns one can  work at low buffer concentrations. UltraSep ES PHARM SPEZIAL bears methylalkyl groups and possesses a selectivity different to that of UltraSep ES PHARM. For strongly basic substances

All UltraSep ES PHARM columns are available also with endcapped materials.

In this manner the following main variables can be used for the optimization of a separation:

For the preparation of buffer solutions it is of advantage to avoid alkali ions. By it the lifespan of the columns will be enlarged. Furthermore there will be no blockage by precipitated salts at high concentrations of organic solvents. Favorable is the adjustment of pH by triethylamine.

PHARM Packings are also qualified for the chromatography of many biologically important classes of compounds, for instance peptides. An example is the tripeptide glutathione. 

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